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Has Anyone Taken Tramadol (Ultram) With An SSRI?

Posted by Brainbeard on July 21, 2009, at 4:50:17

I'm on sertraline (Zoloft) 25mg since a short while. I also take a little (5-20mg) ziprasidone (Geodon) and 15mg (3x5) of Buspar.

I have chronic dental pain that for the bigger part can't be treated or can't be treated yet (while for a big part the causes ARE visible on x-rays). It's complicated, but all you need to know is: I have pain. Since paracetamol (Tylenol) sometimes doesn't take care of this pain, and an NSAID like Ibuprofen is contra-indicated because of drastically increased upper gastrointestinal bleeding risk with an SSRI (although my low dose of Zoloft might prevent that), I asked my doc to prescribe something else for the pain. I mentioned codeine, tramadol and gabapentine. He agreed to prescribe Tramadol. 'It's no problem to take it with an SSRI', he said over the phone. I didn't feel like engaging in a pharmacological discussion once more, so I just agreed, while I knew of course that this isn't true.

Now, my question (yes, we're approaching the question now) is - I know that there have been cases reported of serotonin syndrome when SSRIs were mixed with Tramadol. I also learned that the seizure threshold can be lowered dramatically by combining Tramadol and an SSRI, and I know of at least one (informal) case report. I probably should have discussed this with my doc, but I was already happy that he even prescribed anything.

So, my question is: has anyone succesfully combined Tramadol with an SSRI?

Thanks.


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poster:Brainbeard thread:907706
URL: http://www.dr-bob.org/babble/20090721/msgs/907706.html