Posted by Brainbeard on July 10, 2009, at 5:45:19
In reply to Fluoxetine and noradrenaline, posted by tensor on June 30, 2009, at 23:35:13
I don't want to post the same message twice, but I think this post in another thread is relevant to this thread as well: http://www.dr-bob.org/babble/20090709/msgs/905985.html. To summarize: the first mechanism through which Prozac elevates noradrenaline levels is 5HT2C-antagonism. Prozac's 5HT2C-antagonism is stronger than its serotonin reuptake inhibition, which means that at low doses, Prozac will hardly boost serotonin at all, but will significantly boost noradrenaline (as well as dopamine).
poster:Brainbeard
thread:904120
URL: http://www.dr-bob.org/babble/20090709/msgs/905987.html