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Re: Question about med combinations

Posted by Brainbeard on June 21, 2009, at 7:03:12

In reply to Re: Question about med combinations, posted by morganpmiller on June 20, 2009, at 1:45:18

Oof, just worked my way through these posts. Wish I'd had some Adderall. But I've reached the end of the thread alive (and awake).

I think Bleauberry is right in saying that SRI or serotonergic action is missing. And I personally feel that lowering the nortriptyline might be important. Nortriptyline can be very effective for sleep in doses as low as 25mg. On higher doses, its noradrenergic stimulation might start to disturb sleep.

One SSRI that I'm missing here and which deserves mentioning, is Luvox (fluvoxamine), since Luvox is the most sedating SSRI and thus the one most likely to help with sleep. When I combined it with 25mg nortriptyline and 10mg of clomipramine (Luvox raises clomipramine blood levels enormously), I slept like a log.

I wouldn't take the combination of meds you were on when you felt better as a starting point, since you may have felt better for completely different reasons than the meds you were on. Unless you are sure it were the meds.


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URL: http://www.dr-bob.org/babble/20090620/msgs/902397.html