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Re: What are TCa's like?

Posted by linkadge on June 15, 2009, at 6:59:41

In reply to What are TCa's like?, posted by newo38 on June 15, 2009, at 2:22:19

TCA's do not feel like celexa at all (imho). The only one that might feel remotly like celexa is clomipramine.

The TCA's all have affinity for the serotonin and norepinephrine reuptake systems. Some TCA's are more selective to norepeinephrine (nortriptyline, desipramine) some to serotonin (clomipramine) and some are about equal (imipramine).

In my opinion they generally have a lot more antidepressant umph. They can be better for dealing with apathy and anhedonia than SSRI's.

They may feel a little sedating (or activating) at first, but these side effects diminish somewhat over time.

Chosing a TCA will depend mainly on your baseline symptoms (typical vs. atyipcal depression) and / or level of insomnia and/or anxiety.

Linkadge


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