Posted by bulldog2 on June 1, 2009, at 14:22:41
In reply to Chemist question....Larry?, posted by bleauberry on May 31, 2009, at 17:00:58
> So, I would like to try a restart of Milnacipran. I prefer the European ones I have because they are powder I can empty from colored capsules. The USA version, Savella, is in tab form with FDA red, aluminum, and stuff that is not cool with me.
>
> Description of Savella, Milnacipran:
>
> "Milnacipran hydrochloride is a selective norepinephrine and serotonin reuptake inhibitor; it inhibits norepinephrine uptake with greater potency than serotonin. It is a racemic mixture with the chemical name: (±)-[1R(S),2S(R)]-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride.
>
> Milnacipran hydrochloride is a white to off-white crystalline powder with a melting point of 179°C. It is freely soluble in water, methanol, ethanol, chloroform, and methylene chloride and sparingly soluble in diethyl ether. It has an empirical formula of C15H23ClN2O and a molecular weight of 282.8 g/mol."
>
> My question is:
> Can I mix the contents of a 50mg capsule in a measured glass of water and drink custom sized doses? That would be a whole lot more accurate than trying to divide up little piles and reload them in empty capsules, which is what I did previously.
>
> My intended starting dose will be extremely low. Last time I only did 6.25mg twice a day and got some fairly impressive results at just 2 weeks. Not bad for someone who failed ECT. Good drug. Difficuty going pee was bad and is what had me stop the med. This time I want to start even lower, give it a month or two, and hopefully allow the adrenergic receptors in the bladder department to adapt, and then go up in dose...if I need to. If the results are anything like last time, I will stay at the miniscule dose and be plenty happy with it.
>
> My whole plan depends on getting small doses as accurately as possible, so I am hoping I can mix into water or juice or something readily available to a non-chemist.
>
> Water? Juice? Other? What's best to mix it in? How long does one think it would stay good in the fridge?
>
> Thank you very much!
>drugs of this class my neutralize the pee effect of minalciprin
poster:bulldog2
thread:898650
URL: http://www.dr-bob.org/babble/20090531/msgs/898799.html