Posted by SLS on May 28, 2009, at 12:18:34
In reply to Re: Starting Namenda for OCD, posted by greywolf on May 28, 2009, at 11:36:34
> Thanks, Scott. Already tried Lamictal twice without success.
I forgot about Topamax (topiramate). It also inhibits glutamatergic hyperactivity, albeit in a different way than the others. Topamax is a AMPA/kainite glutamate receptor antagonist. It does not work at the NMDA receptor. If I remember correctly, there is a complex relationship between the functioning of NMDA receptors and AMPA/kainite receptors. It might make sense to attack both receptors at once. I am hoping the same thing for my bipolar depression.
- Scott
poster:SLS
thread:898067
URL: http://www.dr-bob.org/babble/20090524/msgs/898100.html