Posted by SLS on May 27, 2009, at 6:11:21
In reply to Re: memantine with other drugs, posted by Elanor Roosevelt on May 23, 2009, at 20:45:43
> Scott
> how are you feeling?
> my mom's doctor agreed to get her off the namenda
> he seemed to think that the success rate over long periods of time was not so greatOops. Sorry Ms. Roosevelt. I didn't mean to ignore your post.
The NIMH concluded that Namenda was ineffective for treating depression when used as monotherapy. Of course, this doesn't preclude it from being effective when it is combined with other drugs.
My personal experience with the drug has not been stellar. It definitely made my depression worse. I experienced a significant rebound improvement when I discontinued Namenda. So far, I haven't seen anyone else have a robust antidepressant response to this drug.
I am thinking about trying Topamax for two reasons:
1. Topamax reduces glutamatergic neurotransmission, as does Lamictal. I respond significantly well to Lamictal, although not robustly.
2. My last experience with Topamax was a positive one. It produced a mild, but stable antidepressant effect. This time, however, I would be taking different drugs along with it.
I don't think that Namenda is a demon drug. It very well might help someone with depression when used as an adjunct to other drugs.
It does seem that Namenda is at least moderately effective to treat OCD.
- Scott
poster:SLS
thread:895522
URL: http://www.dr-bob.org/babble/20090524/msgs/897894.html