Posted by linkadge on May 20, 2009, at 20:59:29
In reply to Re: This study makes no sence » linkadge, posted by SLS on May 20, 2009, at 10:44:34
>Ask the rats if they are enriched.
Well, the study suggested they have a higher rate of hippocampal neurogenesis as well as cellular survival. They also showed higher levles of BDNF, these kinds of synaptic differences are seen in other forms of environmenal enrichment.
>I have already addressed this issue with the >concept of a lack of neuronal pruning, >ESPECIALLY in the context of increased BDNF.
You havn't "adressed" anything.
>Too much BDNF at critical periods of >development? Too much neurogenesis at a time >where pruning should be occurring?
What constitutes too much BDNF? BDNF is not just a factor promoting neurogenesis, it also affects the way that neurons survive and connect with other neurons. Mice with elevated levels of BDNF perform better than regular rats on several tests of memory and cognition. Some studies suggest that elevated hippocampal BDNF confers a phenotype resistant to depression.
This study doesn't make sense to me. I don't really uderstand what you are trying to say (no offence) - or see how it proves anything. I think I the explaination for this phenomina is far beyond my understanding.
Linkadge
poster:linkadge
thread:896668
URL: http://www.dr-bob.org/babble/20090515/msgs/896881.html