Posted by linkadge on May 14, 2009, at 8:27:34
In reply to Re: Little more » linkadge, posted by SLS on May 14, 2009, at 6:23:44
>Interesting. That is the second abstract I have >seen that casts doubt on the need for 5-HT1a >receptor upregulation to produce an >antidepressant response.
>It is an easy argument to make that the probable >heterogeneity of diatheses of phenotypic >depressions allows for multiple mechanisms to be >contributory to a therapeutic effect across the >population. Post mortem studies of humans with >MDD have demonstrated reduced 5-HT1a binding.
And some studies have demonstrated increased binding.
http://www.futurepundit.com/archives/001768.html
>There are so many different reported biological >correlates of Axis I affective disorders, it is >difficult to invest in any one of them.True
Linkadge
poster:linkadge
thread:895287
URL: http://www.dr-bob.org/babble/20090505/msgs/895740.html