Posted by SLS on May 12, 2009, at 7:00:02
In reply to is it a must that ssris poop out ?, posted by sdb on May 12, 2009, at 4:37:00
> is it almost for sure that ssris do poop out
It sometimes looks that way if you were to gauge the answer to your question by what we observe in the population who post on Psycho-Babble. My guess is that it is precisely because those people who have failed to continue to respond to SSRIs are attracted here in such large numbers. In other words, I think that it is possible that more people continue to respond than fail to continue to respond to SSRIs in the general population. I suspect, though, that the SSRIs do have a greater liability for losing their effectiveness than the older drugs and the SNRIs.
You might consider combining a SSRI with desipramine or nortriptyline; both of which are tricyclic antidepressants (TCA). I am not sure, but I would bet that doing so could yield a more robust therapeutic response and help protect against "poop-out".
- Scott
poster:SLS
thread:895326
URL: http://www.dr-bob.org/babble/20090505/msgs/895335.html