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Re: Mirtazapine and RLS » sowhysosad

Posted by West on May 4, 2009, at 16:03:56

In reply to Re: Mirtazapine and RLS, posted by sowhysosad on May 4, 2009, at 14:43:51

I thought that was what it could be, but since it was just in the legs i think it's more likely to be rls. Akithisia is a whole body feeling and of not being able to control it.

Of interest on mirtazapine: ken gillman seems unconvinced it has any significant serotonergic action at all, claiming serotonin syndrome is almost impossible to induce even at uber overdoses; there is however at least one documented case of SS i know of in somebody taking it alone and with nothing else on board.

How do you find it in comparison to the SSRIs in regards to your depression? I imagine there's less apathy involved since mirt increases noradrenergic and (in theory) dopaminergic tone. I'm pretty much resigned to taking an ssri for life since i rapidly decline without it.

I have never heard of dopamine depletion with SSRIs, that does not sound good at all.

 

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poster:West thread:894213
URL: http://www.dr-bob.org/babble/20090426/msgs/894231.html