Posted by sowhysosad on April 10, 2009, at 14:37:11
In reply to Re: SSRI or 5HTP with movement disorder?, posted by desolationrower on April 9, 2009, at 20:26:50
> well it would, if it were true. but while its possible there are other things most drugs are doing, there really isn't much evidence for it. and i thought the problem was related to 5ht in this case anywya?
> -d/rNah, the most likely suspect is dopamine depletion in this case. My neuro says he sees it most often with citalopram and escitalopram as they're the most selective SSRI's. There's also a big psychogenic component too though, and the symptoms are getting considerably better with hypnotherapy.
Is there not some evidence for other action of SSRI's, like 5HT receptor blockade and D2 supersensitivity? For example:
http://www.ionchannels.org/showabstract.php?pmid=9050900
http://biopsychiatry.com/dopamine-d2.htm
poster:sowhysosad
thread:887980
URL: http://www.dr-bob.org/babble/20090408/msgs/889824.html