Posted by bleauberry on March 26, 2009, at 17:17:24
In reply to Seroquel Panic Help!, posted by Zana on March 26, 2009, at 8:14:06
> Anybody else out there taking seroquel wake up in a panic?
In my earlier days on antipsychotics they did not do this to me. Now Zyprexa, Seroquel, or Abilify do. It is quite frightening isn't it? Harmless enough, yet profoundly uncomfortable. Makes me wonder what kind of trauma I am subjecting my nervous system and hormones to when I just tough it at each waking.
>I take remeron, seroquel and klonopin at night. When I was taking remeron without seroquel I would sleep for 9 hours and wake up fine - depressed but not panicked.
Despite the distorted view of remeron being a great antidepressant in clinical trials, few clinicians I am aware of have been able to duplicate those good results. When they do, it is usually in the 45mg range. If it isn't helping with your depression, logic begs the question why continue with it. Maybe a decent sleep med for you, but obviously not much else. Maybe consider adding a different antidepressant?
>Since adding the seroquel I wake up after 6hrs, take a klonopin to try to get back to sleep and then wake up in this terrible, panicked state. I know I could just get up but even though the seroquel is helping with my depression I am still too depressed to face such a long day.
Too depressed to face the day despite those particular meds. Yeah, I would definitely keep putting a lot of time and faith into those meds. Not. It boggles my mind sometimes how people just stay with something that obviously is not bringing them anywhere close to a 50% improvement (clinical study success), or better, remission.
But I have been guilty of that in the past too. Just not any more.
> Any help will be apprechiated.
> ZanaIt is just my theory without any backing that when antipsychotics cause that panic, or maybe something similar in the akathisia department, it is a complex interplay between the stimulated norepinephrine/adrenaline release (alpha2 antagonism) in combination with unknown weird things that happen when dopamine and serotonin receptors are blocked, in addition to the effects of these meds on cortisol.
In any case, I think your body and your own logic is telling you this whole cocktail is off in the wrong direction for you. Maybe clonopin is a keeper, I don't know but you do, but the others I personally would already be planning my weaning strategy to get off and planning my next med to try.
But that's just me. Just sharing another's view.
One final bit of advice. Insist on brand name meds. They are worth the cost in many cases.
poster:bleauberry
thread:887060
URL: http://www.dr-bob.org/babble/20090322/msgs/887120.html