Posted by metric on March 26, 2009, at 12:29:15
In reply to Providgil Could Be Additive Study Says, posted by Phillipa on March 23, 2009, at 19:22:15
It's long been known that modafinil is a DRI. The significance of this property has been downplayed by its manufacturer for good reasons -- clearly a wise decision.
As long as mood-elevation is viewed as an adverse drug effect, it shouldn't come as a surprise that none of the "antidepressants" work (except the old unselective MAOIs, which are plagued with so many side-effects that they're useless in all but the most desperate cases).
Modafinil is probably the closest thing we have to an "antidepressant" in the U.S. Of course it's only used off-label for that purpose, because only non-mood-elevating "antidepressants" are permitted; how silly is that? "Antidepressants" are extensively screened prior to marketing to ensure they lack "abuse potential". A drug has "abuse potential" if it elevates mood. The contradiction is irreconcilable. Think about it.
A shift in public attitude -- and attendant change of laws -- is sorely needed in order for effective pharmacological management of depression to become routine.
poster:metric
thread:886706
URL: http://www.dr-bob.org/babble/20090322/msgs/887082.html