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Re: Agomelatine

Posted by Niltiac on March 24, 2009, at 14:14:19

In reply to Agomelatine, posted by Bob12 on February 28, 2009, at 11:01:05

Hi Bob,

I was part of a clinical trial with agomelatine last year for GAD and was on agomelatine for 4 months. At the beginning I was extremely skeptical, which I think could be attributed to being a neuroscience PhD student. I've done preclinical research in the area of antidepressants for years and my knowledge of the field has led me to be very questioning towards such medications. But the effects of agomelatine really forced me to change my point of view. Before this trial I had never taken anything for my GAD and I found that I started to feel different after about 2 weeks. The experience was absolutely life changing and I've never been able to replicate it with other medications since.

The thing that made the biggest impression was the quality of my sleep. My sleep was incredible. I can't even fully describe it. I hadn't even realized that my sleep was so bad until it changed. I would wake up feeling absolutely refreshed and energized. I would be very alert and awake all day and right up until bedtime. My sleep was very regular and very efficient. I found I needed much less sleep and felt better than ever.

My GAD symptoms also pretty much disappeared with absolutely NO side effects. And I appreciate this so much more in hindsight because I seem to be VERY sensitive to side effects of SSRI's and I've been struggling in vain since I stopped agomelatine.

When I came off the drug I wasn't aware of it (after 4 months of medications we started a period of double-blind placebo), but it was obvious within the first week. I didn't experience any actual withdrawal symptoms, I just went back to the way I had been before. My sleep was terrible and all my GAD symptoms came back over the course of a few weeks.

Anyway, I'm desperate for agomelatine to be approved in Canada and I've gone from a skeptic to a full supporter due to my first-hand experience of it's positive effects.

Niltiac


> Hi,
> Can anyone describe their experiences with Agomelatine?
>
> thanks
> Bob


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