Posted by SLS on March 22, 2009, at 10:34:39
In reply to Re: Vilazodone - SSRI + 5HT1a partial agonist, posted by dcruik518 on March 22, 2009, at 9:18:52
> Hmm... sounds interesting. Does it work similarly to Trazodone and Serzone? I know they have a dual serotonergic action as well, just can't remember what exactly it is. Do you know when it's expected to be released?
Actually, the drug is similar to gepirone, an investigative drug that has failed to be approved by the FDA. I believe that the reason buspirone can act as such a good augmenter of antidepressanats is because of its ability to act as a partial agonist (stimulator) of 5-HT1a receptors.
The article said that the drug company will submit vilazodone for approval later this year.
- Scott
poster:SLS
thread:886518
URL: http://www.dr-bob.org/babble/20090322/msgs/886531.html