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Nortriptyline on its own - what to expect?

Posted by hansi555 on March 20, 2009, at 12:16:32

Hi

I am currently building up my Nortriptyline dosage from 85 mg to 125 mg.
Before that I was taking 20 mg Lexapro and 85 mg Nortriptyline resulting in a constant can-not-get-100%-happy-feeling, my PD said that Lexapro was to blame for this and we therefore decided to go for Nortriptyline on its own, tappering off Lexapro over a 7 week period.

When tappering to around 8-12 mg Lexapro (and still 85 mg Nort) I was feeling quiet good for several weeks, I was my own real me.
After reaching around 3-4 mg Lex and below my mood has been more and more sad/depressed and its now 4 weeks since I took the last Lex pill.

A blood test when taking 85 mg of Nort only showed a concentraion of 157 and the therapeutic window is 190 - 570. When I was on 20 mg Lex and 85 mg Nort the concentration was 292.

So the logic says something like 125 mg of Nort...

But I have this feeling Nort will not work properly on its own.
What are your experiences with Nort on its own?

I know that Nort is weak in regards of Serotonin effect but what does this mean?

How long should I wait to see the full effect of Nortriptyline?

I have gone from 85 to 125 mg in 20 days, and so far it hs been more downs than ups..

I am also taking 15 mg Remeron at bed time for sleep.
I am stress burnt-out and have unipolar depression.

All comments welcome


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poster:hansi555 thread:886244
URL: http://www.dr-bob.org/babble/20090313/msgs/886244.html