Posted by Dee2 on February 23, 2009, at 23:32:27
In reply to Re: People taking rocket fuel » Dee2, posted by Neal on February 22, 2009, at 22:09:40
> "Remeron will help most people sleep better, just watch out for too many trips to the refrigerator"
Yep, I did get the odd hunger for the first few days, but it abated. Guess I'm lucky! I'm a calorie counter anyway, no way I'm putting on weight.So far loving the Remeron/Effexor combo, it's awesome. Pretty nervous from the noradrenergic spike the first few days, due to norepi re-uptake inhibition, but that leveled out. The pill puts me right to sleep at night and I wake up refreshed, not dopey at all the next day.
BTW, I figured out that since I take Effexor, Buspar and Remeron in combination, i'm hitting all of the relevant mood related serotonin receptors!!! Buspar 5ht-1a, Remeron effects 5ht 2 a-b plus 5-ht3, and Effexor hits 5-ht1 a-b plus 5ht-2a.
Norepi activity is triple affected and dopamine double affected, I believe. Nice thing about this effect is that it is receptor specific and the additional norepi load from remeron is on the good norepi feedback loop, not straight up norepi, which would cause agitation.
BTW, if you're a nerd like me you can get this info from a google book search, they have tons of full and partial psychiatry/chemistry texts online. God bless.
poster:Dee2
thread:878905
URL: http://www.dr-bob.org/babble/20090223/msgs/882089.html