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Muscarinic antagonists for OCD?

Posted by psychobot5000 on February 10, 2009, at 23:22:34

So, some researcher or other seems to claim that blocking muscarinic receptors (specifically m4) is possibly helpful for OCD (could this explain why paxil was used preferentially for OCD for a while?). And I know one patient (me), whose OC symptoms partly remit during a dose of benadryl, which is quite an anticholinergic.

Are there other anticholinergic (antimuscarinic, really) drugs out there, that one such as I might use to combat OCD? Preferably something relatively 'clean' in terms of its other effects (i.e. less sedating and antihistaminic than benadryl)? I would be a willing guinea pig to see if any such thing works.

Anticholinergic drugs--which are your favorites?

Thanks for any input,
Psychbot


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poster:psychobot5000 thread:879355
URL: http://www.dr-bob.org/babble/20090203/msgs/879355.html