Posted by psychobot5000 on February 2, 2009, at 21:24:30
In reply to Re: Desipramine vs Strattera adult ADD-SLS/ D/R » JadeKelly, posted by SLS on January 31, 2009, at 11:39:31
> > So if ADD were the primary concern, and depression secondary or minor, which is the better choice?
>
> If he is experiencing any improvement after one week on Strattera, I would be very encouraged.
>
> I would stick with the Strattera and see how that goes. I watched someone with ADD have their depression resolve as the ADD resolved.
>
> Look into clonidine for ADD. It can be used as an augmenter to Strattera or a stimulant. Some people get depressed on clonidine, but it might still be worth a shot. Right now, there are ongoing trials studying the use of memantine (Namenda)for ADD. You might be able to build a treatment regime around Strattera if it is at all helpful.
>
>
> - ScottI agree with Scott, and would also urge trying to stick to the Strattera for a little while. However, I do think desipramine would be a reasonable option to try, down the line--after strattera is given a chance.
Scott's suggestion of clonidine also seems to me a good one--however, I would suggest that instead of clonidine, your nephew could try its brother, guanfacine. They're almost the same drug, but guanfacine is better-established for ADD. For some subtle reasons involving the two drugs' properties (their binding to alpha 2a receptors, I believe), guanfacine probably works slightly better. It's a non-addictive option that's FDA-approved for ADHD.
(best of luck)
psychbot
poster:psychobot5000
thread:875152
URL: http://www.dr-bob.org/babble/20090104/msgs/877729.html