Posted by bleauberry on January 20, 2009, at 18:46:48
In reply to What causes AP weight gain?, posted by SLS on January 19, 2009, at 11:59:19
Scott, I couldn't begin to remember where I saw it. But there was a very lengthy detailed thing I read a few months ago about APs. It looked into how they impacted about 50 different genes. About half of those genes were either turned on (if they had been off) or turned up in volume, while the other half were turned down in volume or off completely. Some of those genes were identified as the ones being directly related to biochemical control of caloric intake, the genes that make it so easy for some people to get overweight and so hard for others to gain any weight. The APs basically turn up the volume on the weight gain genes. I don't think it has much to do with receptor antagonism. I think it is deeper than that. The paper I read had identified all these genes in minute detail and how different APs influenced them. Zyprexa was obviously the worst.
poster:bleauberry
thread:874936
URL: http://www.dr-bob.org/babble/20090104/msgs/875202.html