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Re: Abilify saved me » theo

Posted by SLS on January 18, 2009, at 21:32:02

In reply to Re: Abilify saved me » SLS, posted by theo on January 18, 2009, at 20:50:41

> How long now have you been on Abilify? Any signs of Tardive Dyskinesia? Abilify worked great for me but I freaked about that.

Tardive Dyskinisia is thought to be less likely with Abilify, primarily because it doesn't accumulate in the motor centers of the brain located in the striatum. It is selective for the mood control centers in the mesolimbic cortex. So, basically, the areas responsible for movement control are not affected.

I don't know if any work has been done in this area, but some people have expressed concern that Tardive Akathisia is a possibility.

> If it helps dopamine isn't it differenent than other AP's that shut dopamine down?

Yes. It increases dopamine activity when there isn't enough and decreases it when there is too much.


- Scott

 

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