Posted by mav27 on January 18, 2009, at 0:32:18
In reply to Re: Long Term SSRI Use Has Destabilzed Me, posted by linkadge on January 16, 2009, at 18:14:07
> Yes, I also agree with the above mentioned description of long term SSRI use. I agree with the notion that the REM disrupting property of the SSRI's could be mediating some of the of these long term effects.
>
> REM sleep is accompanied by growth hormone release. So, supressing REM sleep could have a detrimental effect to long term energy levels, learning, etc.
>
> The SSRI's activate all serotonin receptors in the brain and body, they are not specific to one subtype. As such, there is likely a whole host of strange metabolic and neuroendocrine changes that occur with long term SSRI use. As well, the SSRI's can reduce dopamine release after long term use, which can lead to apathy as well as reduced testosterone release.
>Is there a definate correlation between dopamine and testosterone, you say reduced dopamine can lead to reduced testosterone but can the reverse be true... could high amounts of testosterone indicate there maybe higher levels of dopamine in the brain... ?
poster:mav27
thread:874312
URL: http://www.dr-bob.org/babble/20090104/msgs/874648.html