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Re: I want to switch from nortriptyline to desipramine » desolationrower

Posted by SLS on January 9, 2009, at 7:36:47

In reply to Re: I want to switch from nortriptyline to desipramine, posted by desolationrower on January 9, 2009, at 3:06:07

> hm, good luck with the change.
>
> i think betahistine would be ideal to counter weight gain, but probably not something you could get a doc to do. modafinil might be helpful in its stead, i sort of remember you saying you didn't take it, but a low dose might not bother you?
>
> not sure what else you take, but at minimum i'd suggest
> fish oil
> vitamin d3
> vitamin k2
> magnesium
> sounds like you excercise and i assume eat healthy.
>
> for weight loss also sesamin would be useful especially for triglycerides too, tho some people find it makes them sluggish or less libido. ashwaghadha is interesting, can't think if its ok with your regimine. green tea extract too. i would give it a try. those numbers are scary.

That's a nice list of alternatives, D/R. Thank you. I think I'll try them. My fear is that without knowing it, my consuming any other substances might destabilize me and prevent me from responding to the medication regime. I think I'll wait until I am stable on the desipramine before adding anything.

> also, can't you just ask for plasma level of the tca if you think its not high enough?

If I have to fight my doctor on this one, I will go for blood levels at that point. I have been on desipramine often enough to know where my clinical range lies. One time, I was told to take 450mg of imipramine, and my blood levels still had not exceeded the therapeutic range. As purported in the PDR and other medical literature, most people will need no more than 200mg of desipramine. However, outpatients and people with more severe depressions are encouraged to target 300mg if necessary.

Thanks again.


- Scott

 

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