Posted by Larry Hoover on January 1, 2009, at 22:04:02
In reply to Re: can methylphenidate be combined with SJW? » Larry Hoover, posted by linkadge on January 1, 2009, at 21:02:04
> There are several compounds in SJW which inhibit monoamine oxidase to varying degrees. Was the study you refer to considering the whole plant extract?
Yes, it was. I couldn't find the questionable study, but I found the one that dismissed the earlier work. No one has ever replicated what the first study claimed.
http://www.ncbi.nlm.nih.gov/pubmed/7857511
> Anyhow, I have only heard that Green Tea inhibits MAO-B. Do you know of any studies suggesting it inhibits MAO-A as well.
No, as far as I know, the effect is limited to MAO-B. And very mild.
> Green tea is intersting. There is a 5 fold dopamine boost with green tea. It inhibits MAO-B, COMT and DAT activities. In addition, theanine displays some NMDA antagonist activity. Caffeine also causes dopamine release.
I think the biggest impact arises through COMT inhibition, but I'm sure the combination is potentiated.
> Just DON'T combine green tea with methylphenidate. I'll never make that mistake twice.
>
> LinkadgeI don't use either, but I'll remember your warning.
Lar
poster:Larry Hoover
thread:871806
URL: http://www.dr-bob.org/babble/20081223/msgs/871852.html