Posted by Larry Hoover on December 30, 2008, at 10:15:46
In reply to Re: Actually, that's not what the study found., posted by linkadge on December 30, 2008, at 8:26:31
> Yes but it said they found a trend towards worsening white matter in the SSRI group.
In the discussion, the authors discuss the lack of context of use of the medication, as they did not collect information with respect to diagnoses which led to the use of medication. The loss of white matter might be a direct consequence of the presence of major depression, which would then be more likely to attract treatment with antidepressants. If that is the case, both white matter loss and antidepressant use become dependent variables of major depression, and significant correlation (or trends towards signficance) would be reasonable, if not expected.
The study raises questions, but provides no answers.
Regards,
Lar
poster:Larry Hoover
thread:871107
URL: http://www.dr-bob.org/babble/20081223/msgs/871407.html