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Re: SSRI insomnia, restlessness, poor concentration

Posted by crittercuddler on December 16, 2008, at 3:31:48

In reply to Re: SSRI insomnia, restlessness, poor concentration, posted by desolationrower on December 15, 2008, at 23:56:18

How do 5HT2A antagonists sometimes worsen OCD? I remember reading that the atypical anti-psychotics can do that when used alone and not in conjunction with an SSRI (not sure how)... but I wasn't planning on using one alone.

That would be really lousy if that happened to me because I don't see any other options for me other than to try an augment an SSRI or a SNRI with an SARI, the TCA nortriptyline, or an atypical anti-psychotic in order to help the agitation, anxiety, insomnia, muscle jerks... etc.... and ALL of those have some kind of 5HT2A antagonism.

From what I read, the SARIs are the strongest 5HT2A antagonists (nefazodone and trazadone) and I after that I don't know where the atypicals (like Seroquel, Risperdal, or Zyprexa) and the TCA nortriptyline would fall into order at.

All the drugs I am left to work with (if I cut out SSRIs and SNRIs all together) have 5HT2A antagonism to some degree. Except Buproprion and I don't see that helping me by itself with major depression and OCD.

Ugh... I am so tired. My brain is fried. No more research or thinking about this tonight. I have been looking at this stuff so long my understanding is starting to regress because I am so exhausted.

I will let you all know how it goes at the doctor tomorrow.

Oh, btw, I made some suggestions to NewQuestions.... maybe you could swing by that thread to check them and see if they are right.

????? Thanks. :-)


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Psycho-Babble Medication | Framed

poster:crittercuddler thread:868434
URL: http://www.dr-bob.org/babble/20081214/msgs/869053.html