Posted by bleauberry on December 6, 2008, at 17:00:23
In reply to Strange shift in 5HT tolerances, posted by zzz7 on December 6, 2008, at 13:51:54
Me too. I wish I had some explanation or suggestion for you.
I never went to real high doses like you did, but I was on regular doses for a decade. Then after strange developments, paradoxical reactions, poopout, and failed ECT, I am super sensitive as you are. Even a mere 2mg lexapro had me on my knees in uncontrollable tears within 3 days. Anything DA helps a slight bit, but then again, just tiny amounts. Any more and things get worse.
Very strange phenomenon.I suspect somewhere along the line receptors just got reconditioned in sensitivity from their artificial environment, or genes got reprogrammed, or something weird.
Interesting about sand sized grains of lexapro. I could try that. :-)
The only med I have been able to tolerate is low dose Milnacipran. Starting dose is 25mg, therapeutic dose is 50mg to 100mg, max is 200mg, but I felt it extremely strong at just 12.5mg.
While 5HT and DA seem messed up somehow, NE seems in better shape. Maybe all those meds didn't mess with NE too much?
Anyway, you aren't alone in this weird thing.
poster:bleauberry
thread:867043
URL: http://www.dr-bob.org/babble/20081204/msgs/867080.html