Posted by JadeKelly on November 2, 2008, at 2:38:02
In reply to Re: Tianeptine and Agomelatine, posted by missmolly on October 19, 2008, at 17:57:20
> Hello - I just wanted to say that I have been following your posts, and I appreciate the updates on your experience with Tianeptine. I am going to begin taking Tianeptine next week for the first time - although I have no current or history of depression. I am taking it because I have Huntingtons Disease - a heredity neurodegenerative disorder. HD's first effects on the brain are atrophy of the hippocampus - much the same as is seen in the brains of those who have major depression. In fact, the first symptoms of HD are usually depression - although I am not yet symptomatic. My neurologist has suggested I begin a Tianeptine regimine- as more of a 'hail mary pass' that this will delay the onset of the disease (other SSRI's are currently in clinical trials for the treatment of HD-but tianeptine has shown less side effects and similar neuroprotective benefits). There is currently no cure, and no treatments for HD. It is always terminal - so I am willing to try just about anything. I would greatly appreciate any information on expected side effects - or any predictions on what this will do to my mood, etc - as I am not depressed. I am in the US - and although my doctor is quite progressive, he doesn't seem to have much experience with this medicine either - so I'm trying my best to educate myself.
>
> Many Thanks to you all for sharing!
>
> ~MHi Miss Molly, I am terribly sorry to hear of your (recent?) diagnosis. You are most resillent to have dodged any depression so far. From what I've read, sounds like you caught it early and could have a long time to figure this out, especially with all the new drugs and discoveries coming our way. It was your doc who advised Tianeptine? If its an obvious choice for your condition, I wondered why it sounded like he didnt know much about it? Also, I know there aren't a lot of treatments available for this disease right now, but what about selegiline, if the tianeptine doesn't work, or, if they can augment each other? Seems Parkinson's is similar in its symptoms? Well I'm not a Doc, but I do hope you get the BEST DOC because I've seen it make the difference. I only mention selegiline because I know it to be neuro-protective, works well for depression for many (me), and may reduce symptoms. Not sure doses would be compatible for each symptom, but worth asking, right?
Hope to see you post again with your progress!!
Best wishes-Jade
poster:JadeKelly
thread:855890
URL: http://www.dr-bob.org/babble/20081027/msgs/860336.html