wellbutrin PI » theo

Posted by azalea on October 31, 2008, at 13:38:12

In reply to Re: Prozac, should i switched to Wellbutrin?, posted by theo on October 30, 2008, at 21:03:21

Theo,
I checked the prescribing info and here's what I found:
CLINICAL PHARMACOLOGY
Pharmacodynamics: Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine and dopamine, and does not inhibit monoamine oxidase or the re-uptake of serotonin. While the mechanism of action of bupropion, as with other antidepressants, is unknown, it is presumed that this action is mediated by noradrenergic and/or dopaminergic mechanisms.
I'd be interested to read the source indicating that bupropion affects serotonin. I'm not saying you're wrong, just never heard that before.
> Actually it does slightly affect serotonin, check out the prescribing info.
>
> > Wellbutrin is NOT an SSRI. It does not affect serotonin at all.

Thread

Prozac, should i switched to Wellbutrin? rjlockhart04-08 10/29/08
Re: Prozac, should i switched to Wellbutrin? » rjlockhart04-08 Phillipa 10/29/08
Re: Prozac, should i switched to Wellbutrin? » rjlockhart04-08 azalea 10/29/08
Re: Prozac, should i switched to Wellbutrin? theo 10/30/08
wellbutrin PI » theo azalea 10/31/08

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