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Re: vynase -any experiences? » WhyandHow

Posted by azalea on October 30, 2008, at 21:40:39

In reply to Re: vynase -any experiences?, posted by WhyandHow on October 25, 2008, at 19:58:53

This article might be useful for you, especially the part about how Vyvanse has reduced abuse liability.

J Psychosoc Nurs Ment Health Serv. 2008 Aug;46(8):19-22.

Lisdexamfetamine: a prodrug stimulant for ADHD.

Howland RH.
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA. HowlandRH@upmc.edu

This article reviews the unique prodrug stimulant lisdexamfetamine dimesylate (LDX, Vyvanse), an approved treatment for attention-deficit/hyperactivity disorder. LDX is an inactive prodrug in which l-lysine is chemically bonded to d-amphetamine. Although its efficacy is not significantly different from that of other stimulants, LDX may be different with respect to potential toxicity and abuse liability. In this article, I will review the short-term controlled studies that were the basis for LDX's approval for both children and adults; the lack of and need for more long-term studies; two double-blind, placebo-controlled, crossover studies that examined LDX's abuse liability; and clinical uses for the drug. The clinical implications stemming from LDX's unique characteristics are also discussed.

>My PA at the local shrink center would never give me a script with my history of drug abuse. I could try to find a doc that would but thought I would try it without a script and decide for myself if the addictive nature would be much of a problem.
>
> At least with Adderall does can be increased but since they made this so somehow you can't really be effected by more than 135 to 150mg, it has left mehigh and dry. If I can ever try it one more time, I will make sure I just take the 75mg and see how well it works after a week.
>
> This whole thing kinda sucks because I really can't afford the arm and leg I had to pay for the stuff on the street. Not only is there obviously no coverage, but I probably paid at least twice as much as it would cost at a pharmacy. And all to give me a huge tease of how well I could feel in life if I was somebody other than me.


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URL: http://www.dr-bob.org/babble/20081027/msgs/860005.html