Posted by shasling on October 26, 2008, at 15:49:25
In reply to Re: Exotic Meds for Treatment Resistant Depression, posted by utopizen on October 23, 2008, at 21:29:00
> > Xyrem isn't exactly the same thing anyway. They changed the molecular formula just a teensy bit, but it was enough to eliminate the euphoria. Just makes you sleepy.
> >
>
> ???
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> Who told you this?
>
> Anyhow, no.
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> As I recall, and so can the entire dorm that evacuated one cold night when some drunk kid pulled a fire alarm, I was so elated on the stuff, I was grinning off into space. While everyone else was sober enough to realize they had just woken up at 3 AM to a fire alarm on a weeknight.
>
> Even the drunk kids were giving me weird looks.
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> Yes, it'll give you elation, at a high enough dose. Which is the therapeutic dose. Before that dose, you get dysphoria. And insomnia. Fun combo, for a sedative, eh?
>
> Oh, did I mention my friends thought on certain mornings I was so depressed to talk to, it would make a widow at a funeral concerned my mood wasn't as great as hers? The docs call that special number "Morning anxiety."
>
>
> Also:
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> IT'S CONTRAINDICATED IN DEPRESSION.
>
> You have depression already, and that 8% dysphoria figure suddenly becomes guaranteed at 100% to you. Keep in mind, depressed patients in all of the trials this data comes from are screened out, and do not enter.
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> Drugs can have a completely different effect on you when you have depression they wouldn't otherwise have.
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>
> It will only compound your problem. Period. It's clinically established to aggravate existing cases of depression. It's even black boxed to prevent patients with mood disorders from getting it prescribed, because it's so likely to cause dysphoria in these patients.
>
>
> DO NOT DO IT. learn from my pathetic stupid waste of a college year.Nobody told me this; you can look them up and see that the molecular formula is slightly differently from GHB, I think one more carbon atom and one less oxygen, something like that. From having used GHB - back when it was legal of course - and now being a long time Xyrem user I can attest they are not identical. My Xyrem experience is: small dose brings a little energy, mid dose: somewhat inebriated but not euphoric, therapeutic dose: sleep. But to each his own. Not worth a debate breaking out.
poster:shasling
thread:854329
URL: http://www.dr-bob.org/babble/20081016/msgs/859364.html