Posted by bleauberry on October 7, 2008, at 20:01:33
In reply to Seroquel XR for depression?? HELP!!, posted by MattSanz on October 7, 2008, at 19:44:28
In clinical studies they tell us what happened at the end of 6 weeks or 8 weeks or whatever, but they rarely tell us what about the 1st. In the minority of studies that do, antipsychotics added to antidepressants usually show positive results within 4 to 7 days. The longer it takes after that time to see any hint of improvement, if there is none in the first week, is fairly indicative of a poorer outcome given a longer time frame. It doesn't guarantee failure by any means, it just doesn't have the odds stacked in your favor.
If your dose were to be increased on anything, I would think the antidepressant dose would be first line, not the antipsychotic.
Right or wrong, just my thoughts. Others will say it takes more time for antipsychotics to work. I just haven't seen that to be true in the real world. If they are going to work, they usually show some hint of that fairly fast.
poster:bleauberry
thread:856295
URL: http://www.dr-bob.org/babble/20081006/msgs/856298.html