Posted by med_empowered on September 29, 2008, at 18:58:48
In reply to Why is Zyprexa so good for anxiety...??, posted by jms600 on September 29, 2008, at 17:57:54
hey. As much as I hate neuroleptics, I see your point. Low-dose zyprexa killed off some major agitation I was experiencing that Klonopin wasn't touching.
My theory: When you take a benzo, you bind to GABA receptors...GABA in turn inhibits the release of various neurotransmitters all over the brain and reduces electrical activity.
Zyprexa inhibits ALL SORTS of neurotransmitters and weakly binds to certain GABA receptors. And it has sedating properties and anti-cholinergic action (which helps prevent EPS and akathisia).
Back in the day, they would have called zyprexa a "dirty drug" b/c it hits so many targets in the brain (by comparison, Haldol is a "clean" drug, given its selectivity for dopamine receptors). I think the non-specificity of zyprexa's action pretty much makes it a "calm the f*ck" down pill in low-doses.
poster:med_empowered
thread:854809
URL: http://www.dr-bob.org/babble/20080926/msgs/854816.html