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Re: another weird clinical trial

Posted by desolationrower on September 25, 2008, at 23:11:37

In reply to another weird clinical trial, posted by mike1975 on September 25, 2008, at 21:33:56

hm, wonder if it is as good as essence of chicken.

Effect of Taking Chicken Essence on Stress and Cognition of Human Volunteers

SUMMARY
Stress is a common phenomenon. Every individual experiences it. There are many ways of combating stress. Stress is necessary for preparation against challenging situations and danger. It is necessary to have stress before a test so that we are prepared. For instance, stress actually motivates students to prepare for examination but excessive stress can lead to poor performance. This study evaluates the effect of a commercial essence of chicken (CEC) on the various parameters related to stress and cognition of human volunteers. CEC is produced by a hot-water extraction process from chicken meat under high pressure condition. It contains concentrated amounts of proteins, amino acids and peptides such as carnosine compared to homemade traditional chicken soup. Due to the unique extraction process, it has been postulated that readily absorbed amino acids and bioactive peptides are present in CEC. In this experiment, we evaluated the effect of CEC in comparison with a placebo and carageenan on a group of stressed medical students before their examinations. Students were divided into three groups at random and given either CEC, placebo or a carageenan drink daily for two weeks. Before and after the two weeks, the students were given a series of tests to assess their mental and physical well-being as well as attention and memory. The tests were the general health questionnaire (GHQ), SF36, digit span, construction of figures, 3-min memory test, comprehension and mental arithmetic. The students who ingested essence of chicken fared significantly better than the other two groups of students. The ability of essence of chicken to control anxiety by distraction and promoting attention and memory is discussed.

Effect of Oral Feeding of Essence of Chicken on the Level of 5-Hydroxyindoie Acetic Acid in the Cerebrospinal Fluid of the Rat
Abstract
The effect of oral feeding of a commercial preparation of essence of chicken (Brand's Essence of Chicken, BEC) on the level of 5-hydroxyindole acetic acid (5-HIAA) in the cerebrospinal fluid (CSF) of the rat was investigated. BEC, when fed to the rat for a period of 3 days, significantly increased the CSF level of 5-HIAA in seven out of 12 animals studied. As the level of CSF 5-HIAA is taken as an indication of 5-hydroxytryptamine (5-HT) activity in the brain, it is possible that BEC increased brain 5-HT activity. This increase was not due to the ingestion of tryptophan, the primary precursor of 5-HT, because BEC contains undetectable level of tryptophan. The data indicate that by causing an increase in brain 5-HT activity, consumption of BEC may lead to the activation of 5-HT-dependent physiological process like sleep improvement, mood elevation, analgesia, facilitation of motor output and regulation of circadian rhythm. However, such a possibility remains to be further investigated.


Effects of Chicken Extract on the Recovery from Fatigue Caused by Mental Workload
Abstract:
Folk wisdom suggests that chicken extract is useful for recovery from physical and mental fatigue. To explore this question, the physiological effect of Brand's Essence of Chicken (BEC), a popular chicken extract used as a traditional remedy, was assessed during recovering from mental stress. We quantitated the blood levels of stress-related substances, and examined the task performance and subjects' mood states during mental workloads. Subjects were 20, healthy male students who have never tasted BEC. They took two bottles of BEC or a placebo (70 ml/bottle) daily in the morning for 7 days. On the final experimental day, two mental workload tests were performed: (A) a mental arithmetic test (MAT; 1600 trials of two or three figure-addition or subtraction for 40 min). (B) a short-term memory test (SMT; 20 trials of memorizing 9 digit numbers). Blood was collected before and after each workload task. After the mental workload, the recovery of mean cortisol level of subjects who consumed BEC was significantly faster than that for those consuming the placebo. The task performance of subjects performing the MAT and SMT was also improved with BEC consumption compared with placebo. According to the profile of mood state questionnaire, subjects felt more active and less fatigued during the workload when they took BEC regularly. We conclude that the extract of chicken has the potential to metabolize stress-related substance in blood and to promote recovery from mental fatigue.
Clinical study on the combined effect of capsaicin, green tea extract and essence of chicken on body fat content in human subjects.
Abstract:
A study was conducted to assess the body fat content of free-living healthy human subjects taking a health supplement containing 0.4 mg capsaicin, 625 mg green tea extract (125 mg catechins and 50 mg caffeine) and 800 mg essence of chicken (CGTE). The subjects were advised to maintain their regular dietary habits and routine physical activity throughout the study duration. Their body fat content was measured before and throughout the trial duration using a hand-grip body fat monitor. After 2 weeks of supplementation with CGTE, the mean body fat percentage of male and female subjects was significantly less than the initial value (P<0.05; t-test). 70.6% of volunteers showed a trend for decreasing body fat content with 4 subjects showing a significant decrease in body fat content over time. The findings suggested that the effects were more prominent in subjects with higher initial body fat content. It was also demonstrated that the resting energy expenditure (REE) of the subjects taking the test samples were significantly increased in groups supplemented with CGTE, compared to placebo group. Thus, the combined thermogenic effect of capsaicin, green tea extract and essence of chicken could translate to a positive clinical effect by reducing approximately 460 g of body fat, following 2 weeks of supplementation and the application of this natural health supplement for excess fat regulation, should be considered.

-d/r

 

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