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Re: Reboxetine vs Effexor, Cymbalta » Tony P

Posted by azalea on September 24, 2008, at 11:28:04

In reply to Re: Reboxetine vs Effexor, Cymbalta » azalea, posted by Tony P on September 24, 2008, at 2:56:47

There's a publication about splitting bupropion. I was unable to access the text of the document, but here's the information if you want to research it or bring it to your MD or pharmacist.

Title: Splitting bupropion extended-release tablets.
Source: American Journal of Health-System Pharmacy. 56(6):575, March 15, 1999.
Author: Cochren, Brad E. BCPP

Were you on a mood stabilizer like Lamictal (lamotrigine) or Lithium at the time bupropion caused mania? Anxiety and insomnia can be a side effect, especially for patient with bipolar who are not also taking a mood stabilizer.

I hope you can get an appointment with an MD soon. Best wishes.

> > Have you tried Wellbutrin (bupropion)? It is generally an energizing anti-depressant, best taken in the morning.
> TP} Yes, tried it several times a few years ago. I like what it does for me, but I am abnormally sensitive to it, so the generally recommended dose (300 mg/day) drives me into full mania (I didn't believe it, but my family let me know - independently - in no uncertain terms that I was acting crazy!) I can tolerate about 25-50 mg/day, maybe 75 mg tops, but it's only available nowadays, in Canada at least, in SR or long-acting dose forms that are larger than that. I tried splitting the tabs, even though you're not supposed to, and that was fairly OK. Still experienced quite a lot of anxiety & insomnia even at low doses. However, maybe it's worth another try. I'll double-check with my pharmacist (who is always very helpful) whether they can get any low dose or splittable short acting tabs.
>
> My MD is away but I'm going to see whoever's on duty at his clinic today or tomorrow, and I have an appointment with a government-funded counselor that I hope will lead to a referral (fairly promptly) to a staff psychiatrist. Experimenting with a statistical sample of one is interesting for a while, but internet drugs are e-x-p-e-n-s-i-v-e, even presuming you find a reliable source, whereas at least some of my meds are covered by the govt. (not Cymbalta, though, - it's too new in Canada & is probably being classed as a "me-too" substitute for Effexor).


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poster:azalea thread:853657
URL: http://www.dr-bob.org/babble/20080915/msgs/853784.html