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Re: seroquel and memantine in psychosis - PLEASE » bleauberry

Posted by yxibow on September 18, 2008, at 5:30:32

In reply to Re: seroquel and memantine in psychosis - PLEASE » Jeroen, posted by bleauberry on September 13, 2008, at 17:48:34

From my own experience with Seroquel, and a host of other things, and a memantine trial for my memory loss problems, when I reached 20mg, something started happening with my mm... I can't characterize it as exactly psychosis but things were definitely wrong in my worldview, I was more disconnected than I am normally.


This is only one case view, so don't take it as whether you should or should not take Namenda, but I'm not quite sure why you want to continue to want to try it. It is a noncompetitive NMDA antagonist. So is amantadine. But other things that antagonize NMDA include ketamine as well. Confusion is a possibility with Namenda, but that takes into account I suppose the mostly elderly trial population if I remember.


Blunting is a part of just about all antipsychotics to a varying extent in people. It is probably a wanted thing actually for those who are heavily hearing voices and the like but it generally is unwanted because one feels a bit disconnected and out of it.

Some people take caffeine -- but that causes problems with the sleep cycle too, and I'm not advocating that as a solution.

There's Provigil, and other things, but some stimulants can aggravate psychosis, so that would be my caution I guess.


-- best wishes

Jay

 

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