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Re: Glycine As a Primary Antipsychotic

Posted by ILADVOCATE on September 6, 2008, at 17:55:07

In reply to Re: Glycine As a Primary Antipsychotic, posted by JDx on September 6, 2008, at 17:33:48

> > I am on glycine, 24 grams under the care of a psychopharmcologist and have obtained a full recovery. It is a new generation of antipsychotics in study, the glutamate antagonists. My psychiatrist is seeking to publish the results in a psychiatric journal. Glycine is available over the shelves but should only be taken under a psychiatrist's care. This generation of antipsychotics cannot cause tardive dyskinesia,which I have from the previous antipsychotics in severe forms including tardive psychosis which is also is study, weight gain, diabetes or extra pyramidal side effects and does not cause cognitive blunting but is actually helpful on cognitive and negative symptoms of schizophrenia. The only antipsychotic currently available that cannot cause tardive dyskinesia, which can be masked as it is occuring, is Clozaril and I could not tolerate its severe side effects. The current studies use glycine as an adjunct but my psychiatrist has obtained favorable results as a primary antipsychotic. This is part of a new generation of antipsychotics in study that have shown extremely favorable results and will eventually replace the current medications. There is a symposium on new medications in development that anyone reading this should consider attending to find out about new antipsychotics that are being studied:
> > http://www.narsad.org/help/campaign/publicannouncement.html
>
> I am on 60 grams of Glycine for half a year. I am daignosed with simple Schiophrenia (only negative simptoms).
> I can say that for me Glycine doesn't improve negative simptoms at all, and it is only improve memory and attention .

Clearly the studies have to go forward and of course not everyone will benefit as much as I did. There are other glutamate antagonists in study as well that are being used as primary antipsychotics (one by Eli Lilly will hit Phase III next year) unlike glycine which in official studies is only used as an adjunct. As well there are other classes of antipsychotics in development besides glutamate antagonists. Its good to hear of other people's experiences but I do hope that research pans out as regarding medications that will replace the current dopaminergic (standard) antipsychotics because of their severe long term side effects. The only thing that I found that was not done in the study was that I had to titrate the dose of glycine to every few hours because when I took it all at once I just felt sick and then it would wear off and I'd get psychotic. Plus its activating and it would keep me up at night. Again this is still a study and they have to finalize what is going on.


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poster:ILADVOCATE thread:850659
URL: http://www.dr-bob.org/babble/20080903/msgs/850683.html