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Parnate Trial - keep going or call it a day

Posted by Justherself54 on August 27, 2008, at 10:10:48

This is week 13 for me and I've been at 50 mg. for 2 of them. I feel no different than I did at 20 mg.
I have had a partial response to Parnate and we were hoping that raising it to 50 mg. would help but nothing yet.

It has helped to keep the depression somewhat manageable, however, I am so lethargic and unmotivated. I just realized that I haven't even turned on the TV in 13 weeks, and I can't focus on reading a book for more than a half hour at a time.

I know from previous threads that augmenting with a TCA could help, but 10 mg of amitriptalyne has knocked me out for 10 hours. The same with nortryptaline.

I've always had a problem with SSRI's when I've tried to revisit them. They just don't work again the way they used to and this Parnate trial feels the same. It's just not working like it did before. I had previous responses to 20 mg. although at that time I couldn't go any higher due to extreme hypotension.

So what say ye, learned friends..I see pdoc next week...

 

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poster:Justherself54 thread:848578
URL: http://www.dr-bob.org/babble/20080822/msgs/848578.html