Posted by med_empowered on August 23, 2008, at 19:21:01
In reply to antihistamines/neuroleptics 2 put somebody sleep, posted by sdb on August 23, 2008, at 15:58:39
Benadryl (diphenhydramine, others) is I think usually dosed out at 25-100mgs/nightly for sleep.
If you're trying to choose between an antihistamine and a neuroleptic for sleep, I'd say go for hydroxyzine. The dosage varies wildly (some people doze off at 50mgs; I used to take 200mgs), but once you hit the right dose its relatively safe stuff...if I recall correctly, higher doses can help with anxiety. It occasionally causes tardive dyskinesia, but I think the risk is a lot lower than with neuroleptics.
In some countries Nozinan (I think that's how its spelled) is used as a sedative. Its a densely sedating neuroleptic; the sleep-aid doses are pretty low, so I imagine the TD/NMS/EPS risks would be pretty small.
Low-dose Seroquel is popular for sleep, but at very low doses the stuff is just an extremely expensive antihistamine. Low dose of Thorazine are still sometimes used as a sleep aid.
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