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Re: reversing poop out effects from Dopamine antagonis » Jeroen

Posted by bleauberry on August 21, 2008, at 16:26:08

In reply to reversing poop out effects from Dopamine antagonis, posted by Jeroen on August 21, 2008, at 2:51:43

While all your focus has been on antipsychotics and dopamine, you might consider that other drugs affect things involved with psychosis as well, and that the whole dopamine-psychosis thing is theory, not fact. There is more to consider. That being said, check this out...

Psychotic depression:
We found one systematic review (search date 2004, 10 RCTs, 548 people) that compared the effectiveness of drug treatments for people with psychotic depression. [38] Two RCTs included in this review compared imipramine with fluvoxamine (a selective serotonin reuptake inhibitor) and mirtazapine. In the first RCT included in the review imipramine was significantly more effective than fluvoxamine (RR 2.10, 95% CI 1.06 to 4.17, P = 0.03). In the second RCT included in the review imipramine was significantly more effective than mirtazapine (RR 3.00, 95% CI 1.01 to 8.95, P = 0.05). The review found that when data were pooled, TCAs were significantly more effective in treating psychotic depression than non-TCAs (RR 2.36, 95% CI 1.32 to 4.23, P = 0.004). [38]

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URL: http://www.dr-bob.org/babble/20080814/msgs/847568.html