Posted by Racer on August 11, 2008, at 17:28:22
In reply to Re: Nardil or not, posted by Vik07 on August 11, 2008, at 13:08:11
> > On the other hand it boosts serotonin in the brain, which I am convinced is not what I need at all. I am afraid of getting the same symptoms I got from Paroxetine/Paxil.
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>There's a very big difference, though, between the effects of increasing serotonin, and increasing all three catecholamine neurotransmitters. Despite the number of people -- including some doctors, who really should know better -- who say that this symptoms requires an increase in that neurotransmitter, the reality is far less clear. Much research suggests that it's not the levels or activity of any one neurotransmitter, nor even the sensitivity to that neurotransmitter -- the most important part of symptom relief is the ratio between the various compounds. Increasing serotonin alone may lead to fatigue, while increasing the ratio between serotonin and noradrenaline/dopamine might not.
I hope that makes sense.
What I'm trying to say is that your reaction to paroxetine and your reaction to Nardil are likely to be unrelated. Their mechanism of action is very different, and the superficial resemblence -- that they both affect serotonin -- is unlikely to correlate with much similarity in their actions.
Best luck to you!
poster:Racer
thread:845503
URL: http://www.dr-bob.org/babble/20080805/msgs/845567.html