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Re: Make three lists. » SLS

Posted by Tomatheus on August 7, 2008, at 19:47:37

In reply to Re: Make three lists. » Tomatheus, posted by SLS on August 7, 2008, at 19:19:26

> The reason I decided to not include "neutral but intolerable" is because those drugs would be excluded from consideration. The three lists are all about trying to choose drug combinations. I'm sure that knowing the pharmacodynamics of the intolerable drugs might provide some relevant data, but it might be difficult to interpret.

Ok, makes sense.

> I noticed you haven't yet tried a tricylic.

Actually, I've tried clomipramine (Anafranil), but found it to be intolerable after one day due to strong irritability. I wasn't on it for long enough to determine whether it was reducing my depressive symptoms or making them worse, so I didn't include it on any of my three lists.

> Are you bipolar? Have you ever been manic?

My current diagnosis is schizoaffective disorder. My experience with mania is as follows: I cycled in and out of hypomania when I was taking Paxil several years back only at the dose of 60 mg/day. At lower doses, I cycled back and forth between euthymia and depression. I also experienced some manic symptoms when I first became psychotic about a year and a half ago. So, I've had some experiences with mania since my depressive symptoms first emerged eight years ago, but far more experience with depression.

> What about Lamictal? Wellbutrin + Lamictal is a combination my doctor favors, even for unipolar depression.

I think that Lamictal might be worth considering, especially in combination with something like Wellbutrin. I had a partial antidepressant response to Wellbutrin+lithium years ago, so Wellbutrin+Lamictal makes some sense. Thank you for the suggestion.

Tomatheus


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