Posted by bleauberry on August 4, 2008, at 21:37:16
Milnacipran. Wonderful AD. For someone with a frustrating 13 years of FDA med cocktails, and failed ECT on top of it, Milnacipran works.
Problems that keep me from taking it:
1. Severe unrinary retention. Almost went to the emergency room for a catheter.
2. Flare-up of dormant previously cured DeGuerveins Tinnitus (the thumb tendon running up the side of the wrist). It goes away when Milnacipran is withdrawna and comes back when restarted. Several trials to confirm.My theory: A noradrenergic deficit over several years has left my entire biochemistry oversensitive to NE, especially boosted NE from a medicine. My brain loves it, but not my body.
To block the urinary retention of Milnacipran a psychopharmacology book recommends Flomax as a prophalactic against it. Someone else here a couple months ago said Flomax worked for the same problem on Desipramine.
But the squeezing of muscles and tendons? What NE blockers would work for that? I need an alpha or beta blocker, not sure which, or one that does both maybe, that works systemically but spares the nervous system. ??? I have Flomax onhand but haven't tried it yet, and am slightly curious if it might even work on the tendonitis thing.
Any advice on this topic is much appreciated. Alpha blockers are not something I know much about, other than Propranolol for stage fright, and Clonidine often causes depression. That's about all I know.
poster:bleauberry
thread:844229
URL: http://www.dr-bob.org/babble/20080727/msgs/844229.html