Posted by Larry Hoover on August 3, 2008, at 21:13:42
In reply to Re: (STAR-D*) helpful link for more info. » dcruik518, posted by raisinb on August 3, 2008, at 19:07:05
> Interesting! Suggests (as we already know...) this stuff is more complicated than we think. I guess they are hypothesizing that the early meds enable the later ones to work?
No, that's not what the trial demonstrates. It shows a sequence of treatment options that might be instituted if the earlier treatments fail. There is no evidence that an earlier failed treatment predisposes to later success. Instead, subsequent treatment should be selected based on differing mechanism of action, in hopes that the novel approach will work where another had not.
Lar
poster:Larry Hoover
thread:843960
URL: http://www.dr-bob.org/babble/20080727/msgs/844008.html