Posted by linkadge on July 25, 2008, at 16:15:01
In reply to Re: CAN SSRI's CAUSE BIPOLAR TO SHOW UP OR JUST SIDE A » linkadge, posted by Marty on July 25, 2008, at 10:17:12
>It is likely that nobody will receive this Bp4 >diagnostic after only 1 or 2 med induced switch >into mania has it takes many years to confirm >the the sufferer doesn't switch into mania >without a change in meds.
Thats true and unfortunately, many patients will still be given mood stabilizers to treat the AD induced mania. Sometimes these patients don't do well. They don't like mood stabilizers alone since they don't help the depression and the AD alone causes mania, so they end up on both classes of meds. Hopefully they will develop diverse targets for unipolar disorder to see if some of these patients might have fewer side effects on an AD with completely different mechanism. I think the AD's that mess the most with sleep seem to be the ones most capable of inducing mania.
Some people think the AD induced mania is really just a form of disinhibition. The SSRI's can diminish executive function and can sometimes cause reckless or thoughtless behavior. Perhaps thats why wellbutrin has a lower switch rate to mania. It would likely enhance prefrontal cortex function that might leave the user in more control of their moods and behavior.
>My Pdoc, which is the most respected Bipolar >disorder specialist in Canada and the president >of the psychiatrist association of Quebec, >already told me he thought that I was Bp4.I don't even think it should be called bipolar really. I have had manic like responces to certain antidepressants. One of the reasons I think it was a form of extreme executive dysfunction is because I was prescribed ritalin which completely aborted it. You wouldn't expect that with BPI.
>It took me 7 years and 25+ med trial before he >dare to tell me about it.
There is so much that they just don't admit to. They are covering the wellfare of their buisness. It is only feasable to release the side effects of a class of drugs when there is a newer class which is supposed to be better.
>The first time I had a switch into hypomania >when after I had a TOXIC psychosis
>(MDMA/Metamphetamine at a rave party) the >general practinioner I saw prescribed me Paxil >40mg for 2 weeks than switched me to 60mg(!) ... >1 month later I had a new job in the 80,000$, a >new 45k sport car and a new girlfriend swith I >propose to while a short trip to Mexico! ... 1 >month before I was crippled into bed suffering >from intense depersonalization/derealization and >psychosis-grade social phobia which induced me >severe panic attack while seeing people ON TV >having social relation/situation .... an illegal >Drug pushed me into psychosis and depression and >a prescription one pushed me into mania .. a >more than common story these days... so I guess >Bp4 will be a big thing when it become official.Yes, my story was not that severe. Like I said before, when you're on drugs (legal or illegal) you are on drugs. Its really hard to know what combinations can do. The famous BP molecular biologist Dr. Manjii said (in reference to the ability of drugs to precipitate mania), "given the right conditions, it seems that anybody can have a manic episode".
Its just like seizures. There is no such thing as immune to seizures. There are high and low thresholds but given the right conditions andbody can have a seizure.
Linkadge
poster:linkadge
thread:841813
URL: http://www.dr-bob.org/babble/20080718/msgs/842020.html