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Re: How long for an adequate tianeptine trial? » Quintal

Posted by SLS on July 18, 2008, at 5:53:40

In reply to Re: How long for an adequate tianeptine trial?, posted by Quintal on July 17, 2008, at 16:12:25

> I've taken up to 62.5mg a day (5 tablets) on occasion, but more often 3-4 tablets depending on how I'm feeling. I've found I can tailor the dose to my mood as I need it. Some days I only take two tablets.

Don't fix what isn't broken, certainly.

The brain, as well as the rest of the body, relies on homeostasis. To habitually change the dosage of an antidepressant is to never allow the brain to equilibrate. To avoid fluctuations in your depression, I would recommend at least trying to remain on the minimum effective dosage of tianeptine that keeps you stable. That probably means to start at the 4 tablets a day and let it "sink in" for 3 weeks.

Pulsing antidepressant dosages often leads to treatment resistance.


- Scott

 

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