Posted by Racer on July 11, 2008, at 19:41:17
In reply to Off Effexor - compulsive crying and grief, posted by satsumas on July 11, 2008, at 10:52:24
>> Opinions? Anyone have any advice? Would a different class of drugs prevent this sort of emotional blunting
My experience has been that any serotonin reuptake inhibitors blunt my emotions -- even at low doses. My guess is that an effective antidepressant of another class would be less likely to have this effect on you. Maybe the fact that you're in such rough shape on desipramine is a bad sign -- or maybe you just haven't reached a therapeutic dose yet. I've heard very good things about it, and would consider trying it again myself if something could be done to keep my blood pressure up. I hope it works for you.
As it happens, I just asked my psychopharmacologist about this sort of thing -- whether an effective anti-depressant would prevent me from being swallowed up by depression. His words, which I'm taking directly from his email: "... says that being beaten up long enough and/or hard enough can essentially inactivate medication or otherwise eradicate positive medication response." Not the most comforting idea, huh? In fact, not comforting at all...
What he did say which might be more comforting for you, is that TCAs rarely "poop out." If desipramine works out for you, it could be you won't have to go through this sort of thing again. And more news which might also comfort you: I didn't have trouble with emotional blunting on nortriptyline, so desipramine might be more pleasant for you in that area, too.
Best luck to you.
poster:Racer
thread:839250
URL: http://www.dr-bob.org/babble/20080706/msgs/839324.html