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Re: boston globe article on SSRI method of action

Posted by SLS on July 8, 2008, at 5:03:05

In reply to boston globe article on SSRI method of action, posted by aaaaalex on July 8, 2008, at 2:21:47

Good find!

It is hard to believe that these investigators are looking at the whole picture. Their theory sounds to me to be as overly simplistic as are some of the others that have been floating around for years.


> http://www.boston.com/bostonglobe/ideas/articles/2008/07/06/head_fake/
>
> Very interesting read (sorry if this is a repost), though it raises more questions than it answers. If anyone has links to the full studies, I'd love to see them.

I sometimes wonder if the shrinking of certain brain structures isn't a true atrophy; a consequence of the disease rather than a cause. Perhaps depression dysregulates circuits upstream, leading to downstream inactivity. If this inactivity were allowed to persist for years, I imagine there would be at least a few areas of the brain that shrink due to a lack of stimulation. I suspect that the hippocampus is one such area.

Just a thought.


- Scott

 

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