Posted by Maximus on June 10, 2008, at 16:01:43
In reply to Re: Cymbalta -- Not so great for bp depression... » Maximus, posted by Bob on June 10, 2008, at 15:10:45
> I assume you're referring to high dose >Effexor? From what I understand, the dopamine >effect does not become evident until quite high >doses. Even the NE is less pronounced at lower >doses, where the drug is heavily serotonergic.
Not necessarily. I suspect that there are different observations/results between an in vitro and in vivo experiment. At 225 mg and higher you can feel the difference.
Although Cymbalta is a stronger NE reuptake drug than Effexor, the risk to trigger a mixed episode is lower with Cymbalta. You feel more flat on it.
poster:Maximus
thread:834005
URL: http://www.dr-bob.org/babble/20080606/msgs/834021.html